This tool can be used for peer-to-peer, physician-to-patient, and physician-to-caregiver discussions. It allows you to open up a pop-up, hands-on, virtual world right in front of you that discusses the role of inflammatory cytokines in RA pathophysiology, with focus on inhibition of the JAK-STAT pathway. The tool displays the crucial role of chronic inflammation in the RA synovium and guides you through cellular and molecular descriptions, animations, and explanations. The images and animations that are brought to reality can be manipulated and controlled by YOU. It allows you to focus on specific areas and be truly engaged in the learning tool.